From the liner notes

Having fled the social confines of mid-19th century Boston for the wide-open frontier world of Colorado Springs, Dr. Michaela "Mike" Quinn (Jane Seymour) finds a new set of challenges - and rewards - in life as a pioneer. With Byron Sully (Joe Lando) and a growing family to support her, each episode features a rich cast of characters and memorable storylines that bring the timeless themes of the Old West straight into the hearts of contemporary viewers.